Endocrine Abstracts

Introduction: Sarcopenia is a geriatric syndrome that causes age-related changes to muscle mass and function. Lung function is reduced in elderly patients with sarcopenia. We explored whether a mechanically assisted squat exercise improved muscle function and mass and pulmonary function in community-dwelling elderly women with or without sarcopenia.Methods: Participants were recruited via posters or the websites of regional health centers. In total, 76 c...

Abstract: Obesity is one of the well-known initiating and aggravating factor of lymphedema. BMI is typically used to define obesity, but in Asian populations, health risks are elevated at lower BMI levels and abdominal fat may be a better obesity metric. Thus, we assessed the potential association between abdominal obesity and lymphedema severity in postoperative breast cancer patients. Thirty-three women with breast cancer-related lymphedema participated in this study. Arm ci...

Objective: Hyperprolactinemia might be related to weight gain, metabolic syndrome, and insulin resistance. The aim of this study was to evaluate that patients with hyperprolactinemia were higher prevalence of metabolic syndrome than civilian population.Methods: From 1st Jan. 1998 to 17th Nov. 2017, 950 patients newly diagnosed hyperprolactinemia in Pusan National University Hospital, Pusan, South Korea, were selected to enroll in a study conducted on hyp...

Background: Osteoporosis frequently occurs in elderly people and is commonly associated with fall and fractures which leads the increase of morbidity and mortality. Therefore, precise prediction of osteoporotic fracture is important in clinical setting. The objective of this study was to investigate the association between baseline compression fracture and trabecular bone score (TBS) and was to assess the ability of TBS to predict vertebral fragility fracture and changes of vo...

Eating behavior is determined by both homeostatic and hedonic values. We investigated the association of hedonic value with striatal dopamine transporter (DAT) availability sub-regionally. An intravenous bolus injection of 18F-FP-CIT was administered after the infusion of glucose or placebo, and the emission data were acquired over 90 mins. DAT availability, binding potential (BPND), were measured via the simplified reference tissue method. Subje...

Background and aims: The efficacy and safety of dapagliflozin as add-on therapy in patients with type 2 diabetes mellitus (T2DM) and inadequate glycemic control with evogliptin and metformin combinations was investigated.Materials and methods: Patients with HbA1c of 7.0% to 10.5% receiving evogliptin 5mg and metformin ≥1000 mg were randomized to receive dapagliflozin 10 mg/day (n=99) or placebo (n=99) for 24 weeks. The primary end...